What Happens If I Accidentally Took Two 300 mg Wellbutrin? Experts Weigh In
If you accidentally took double dose of wellbutrin 300mg one day, you are not alone, but it is critical to take immediate medical action. Taking a total of 600 mg of Wellbutrin (bupropion) significantly increases your risk of experiencing serious, life-threatening side effects, primarily seizures. The maximum recommended daily dose of bupropion is typically 450 mg. Consuming more than this threshold requires professional medical attention, even if you feel completely fine right now.
Quick Answer: If you accidentally took two wellbutrin xl 300 (totaling 600 mg), contact Poison Control (1-800-222-1222 in the US) or seek emergency medical care immediately. The most significant risk of taking a double dose of bupropion is a severe seizure. Do not wait for symptoms to appear before getting help.
Page Contents
- Understanding the Risks of a Bupropion Overdose
- Can I Sleep If I Accidentally Took 2 Doses of Burpropion?
- What to Do If You Accidentally Took Double Wellbutrin
- Frequently Asked Questions (FAQ)
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Understanding the Risks of a Bupropion Overdose
Many patients frequently wonder, “what happens if i accidentally taken a double dose of bupropion?” Bupropion works differently than many other antidepressants by affecting the reuptake of norepinephrine and dopamine in the brain. Because of this unique mechanism, abnormally high doses drastically lower your seizure threshold. When you accidentally took 2 wellbutrin 300, the concentration of the drug in your bloodstream spikes rapidly, putting your brain at a much higher risk of abnormal electrical activity.
Other immediate side effects may include severe tremors, a racing heart (tachycardia), hallucinations, nausea, extreme agitation, and confusion. If you bupropion 300mg xl accidently took twice in one day 2 pills instead of your prescribed one, the extended-release (XL) formula means the drug will continue to release into your system over a 24-hour period, making prolonged medical observation absolutely crucial.
Can I Sleep If I Accidentally Took 2 Doses of Burpropion?
A very common concern among patients is, “can i sleep if i accidentally took 2 doses of burpropion?” Because bupropion is a stimulating antidepressant with energizing effects, taking a double dose almost universally leads to severe insomnia and intense restlessness. It is highly unlikely that you will be able to sleep comfortably. More importantly, you should never attempt to simply “sleep it off” without consulting a medical professional, as the risk of a seizure occurring while you are unobserved in bed is highly dangerous.
What to Do If You Accidentally Took Double Wellbutrin
If you suddenly realize you accidentally took double wellbutrin, you must follow these steps immediately:
- Do not panic, but act quickly: High anxiety will only worsen your racing heart and agitation.
- Call Poison Control immediately: In the United States, call 1-800-222-1222. Be prepared to provide them with your exact dosage, the exact time you took the pills, your weight, and the specific formulation (e.g., XL or SR).
- Do not induce vomiting: Never try to make yourself throw up unless explicitly instructed to do so by a poison control specialist or doctor.
- Go to the Emergency Room: If instructed by medical professionals, go to the nearest emergency room. They may administer activated charcoal to prevent further absorption or provide preventative medications (like benzodiazepines) to stop seizures before they start.
For those taking different dosages who might ask, “if i accidently took 2 more 150 mg of burproion in the evening, what do i do?” the medical advice remains exactly the same. Taking an extra 300 mg (two 150 mg pills) on top of your morning dose pushes you near or past the safe maximum daily limit, significantly increasing your seizure risk. Contact a doctor or emergency services right away.
Frequently Asked Questions (FAQ)
Will I definitely have a seizure if I took 600 mg of Wellbutrin?
Not definitively, but the risk increases exponentially at doses above 450 mg per day. The risk is considerably higher if you have a history of eating disorders (like anorexia or bulimia), a prior history of seizures, or if you are taking other prescription medications that also lower the seizure threshold.
Should I skip my next scheduled dose?
If you have taken a double dose, you will almost certainly need to skip your next scheduled dose to let the medication clear your system. However, you must confirm this directly with your doctor or pharmacist, as managing your long-term dosage safely requires professional oversight.

